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FAK activator 1
CAS No. 1211825-25-0
FAK activator 1( —— )
Catalog No. M37032 CAS No. 1211825-25-0
ZINC40099027 is a specific adhesion plaque kinase (FAK) activator that promotes gastric mucosal repair in persistent aspirin-associated gastric injury through activation of adhesion plaque kinase, activates human adhesion plaque kinase by accelerating the enzyme activity of the structural domain of FAK kinase, activates cytosolic FAK, and promotes intestinal epithelial wound closure.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 141 | Get Quote |
|
| 5MG | 212 | Get Quote |
|
| 10MG | 353 | Get Quote |
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| 25MG | 569 | Get Quote |
|
| 50MG | 914 | Get Quote |
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| 100MG | 1413 | Get Quote |
|
| 200MG | 1908 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameFAK activator 1
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NoteResearch use only, not for human use.
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Brief DescriptionZINC40099027 is a specific adhesion plaque kinase (FAK) activator that promotes gastric mucosal repair in persistent aspirin-associated gastric injury through activation of adhesion plaque kinase, activates human adhesion plaque kinase by accelerating the enzyme activity of the structural domain of FAK kinase, activates cytosolic FAK, and promotes intestinal epithelial wound closure.
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DescriptionZINC40099027 is a FAK activator. ZINC40099027 promotes FAK phosphorylation, inducing mucosal healing in murine models. ZINC40099027 can be used for Gastroduodenal ulcer disease research.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetFAK
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RecptorFAK
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Research Area——
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Indication——
Chemical Information
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CAS Number1211825-25-0
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Formula Weight449.47
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Molecular FormulaC23H26F3N3O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (222.48 mM; Ultrasonic )
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SMILESO=C(NC1=CC(=CC=C1N2CCOCC2)C(F)(F)F)N3CCCC3C4=CC=C(OC)C=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wang Q, et al. Discovery of Novel Small-Molecule FAK Activators Promoting Mucosal Healing. ACS Med Chem Lett. 2021 Feb 16;12(3):356-364.?
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